General Hospital Spoilers & Preview for the week of April 21–25, 2025, promise explosive twists in Port Charles. From a terrifying hospital plot to romantic regret and corporate chaos, the drama doesn’t hold back. Let’s break down everything coming up in the latest preview clip.
General Hospital Spoilers: Natalia Gets Fired as Secrets Explode
Natalia Ramirez’s world collapses after a major secret surfaces. The women at Deception—Maxie, Lucy, and Brook Lynn—confront her with fury. They’ve just discovered she was once married to the infamous Jenz Sidwell. Although Natalia never thought this connection would come to light, it spreads like wildfire. She’s stunned and blindsided.
Natalia insists she’s not close to Sidwell and wants nothing to do with him. Still, the fallout hits hard. The Deception team doesn’t take chances. They fire her without hesitation, forcing Natalia to face the consequences. As her professional life crashes down, so does her personal support. This could be just what Sidwell planned all along—breaking her down to control her.
Her firing leaves Natalia vulnerable, exactly how Sidwell likes it. If she turns to him for help, it could create an even bigger storm for Port Charles.
Molly Faces a Crushing Realization
Meanwhile, Molly Lansing-Davis thinks things are finally stable with Kristina. Their bond seemed stronger after Ric’s accident. Kristina showed up for her sister, offering rare emotional support. Molly viewed it as a silver lining in a dark time.
But peace shatters when Molly stumbles upon a document that changes everything. The paper appears to be the same one Alexis once drafted to commit Kristina. Although Alexis never followed through, somehow, the document reaches Molly’s hands. It horrifies her and creates fresh tension. The revelation could undo all the progress the sisters have made.
This moment may trigger a painful fallout for the Davis family. Will Molly confront Kristina? Or will she go after Alexis instead?
General Hospital Spoilers: Willow Heads to Germany with Regret in Her Eyes
Across the globe, Willow Tait Corinthos makes a huge decision—she travels to Germany to face Michael. He’s receiving treatment for burns, and the separation between them has grown heavy. Despite signing divorce papers, Willow still feels torn inside.
As they come face-to-face, the spark they once shared could reignite. Michael’s vulnerability might shake Willow to her core. Seeing him in pain could lead her to question everything. Did she act too fast? Will she want a second chance just as Drew Cain enters the picture?
Drew has been patient, but if Willow reconsiders, he won’t hold back. This love triangle may heat up faster than anyone expects.
Sonny’s Hospital Scene Turns Deadly
The most chilling part of the General Hospital Spoilers & Preview clip shows Sonny Corinthos in danger. After undergoing heart surgery, Sonny rests peacefully—until a fake nurse enters. With a deadly syringe in hand, she approaches his IV line. The tension spikes as she prepares to inject him.
But just as she makes her move, Sonny’s eyes fly open. Is he aware of the threat, or is this his last conscious moment? Either way, the situation looks grim. Thanks to Natalia’s loose lips, Sidwell knew about Sonny’s surgery. Now, Sonny may pay the ultimate price. Sidwell’s plot may be deeper than expected. Will Sonny survive the week, or is his empire about to fall apart?
Port Charles is a pressure cooker about to blow. Natalia’s world is crumbling. Molly faces a shocking betrayal. Willow could backtrack on her divorce. And Sonny’s life hangs by a thread. With high-stakes drama and life-changing moments ahead, this week will be unforgettable. Expect fallout, revenge, and emotional fireworks. These stories are just heating up.
The General Hospital Spoilers & Preview for the week of April 21–25, 2025, deliver must-watch drama. Every twist threatens to change everything. From secret betrayals to dangerous plots, the ABC soap is pulling no punches. Don’t blink—Port Charles is on fire. Also, keep coming back to Soap Opera Daily for more updates like such.